Treatment for Pulmonary Hypertension It is important to determine the cause of PH, before the type of treatment is decided. If your PH is caused by another disease, such as congenital heart disease, then your PH must be treated as well as this condition. Treatment for the underlying condition may help control the PH. In the world of PH you will often find two types of treatment approaches are usually discussed: These are terms commonly applied to medical management. However, you should regard these medicines as just one part of an overall treatment plan aimed at improving your quality of life. Increasing emphasis is placed on the crucial role of exercise in the management of PH. This is likely to involve you increasing exercise levels steadily over a period of time. It is also becoming more commonplace for PH patients to enrol onto local pulmonary rehabilitation courses. Either way, expert advice on safe, effective exercise tailored to your situation is available from your specialist PH centre. Conventional therapy (often called background therapy) can include the following: Oxygen Warfarin Diuretics Targeted therapy Calcium channel blockers Endothelin receptor antagonists Phosphodiesterase 5 inhibitors Intravenous Prostanoids Soluble Guanylate Cyclase Stimulators Nebulised Iloprost Selexipag Surgery Pulmonary endarterectomy Atrial septostomy Transplant surgery Many people with PH are treated with both conventional and targeted therapies, although this can be different for different people. Some people with PH may need surgery. How your PH is treated will depend on a number of things, for example how severe your PH is, what type of PH you have, etc.